2x07: "It's Too Late"

When Jesse arrives at his apartment with Ryan Clarke, Liliana Martinez becomes upset and tells Jesse that it is not a good idea for him to be around Ryan. When their argument gets heated, Liliana excuses herself so that she can take a walk and calm down.

When Liliana takes a walk, she places a call to someone in which she demands that something be done about Jesse. After hanging up, she gets on the elevator where she has a strange encounter with Szymon Skubisz. She appears to be frightened by him and says some awkward things before fleeing from he elevator. Joseph teases Szymon about Liliana's reaction to him.

After Jesse leaves to go check on his grandmother, Ryan enters his bedroom and is shocked to see pictures of Julia Taylor plastered all over the room. Liliana enters the bedroom and urges Ryan to leave Jesse alone. She used the pictures as proof that Jesse is not well and tells Ryan that as long as she is present, Jesse will never give up on his obsession with Julia Taylor.

2x08: "Last Night"

When Jesse returns home to find that Ryan Clarke is gone, he blames his grandmother for driving her away. As the argument between him and his grandmother reaches a fevered pitch, Liliana makes a startled admission that leaves Jesse stunned. The reason his mother is mentally ill is because she was raped and she killed the man who did it and that man was Jesse's father. She could not deal with that trauma and went insane. Liliana informs him that he looks exactly like his father.

The next morning, Liliana springs a surprise on Jesse. She has called a psychiatrist to come evaluate her grandson so that she can continue to be his legal guardian in the event that he is not fit to take care of himself. The man, Adam Price, sits down with Jesse to evaluate him.

2x09: "Together"

As Jesse sits at home trying to find a clue in Ryan's past that links her to Julia, he is disturbed by the fact that Ryan doesn't seem to have much of a past beyond five years ago. When Liliana Martinez interrupts him and reminds him that it is his mother's birthday, the two decide to go out for lunch to celebrate.

As they are nearing the diner, Jesse hears music that seemingly entrances him. He heads for the sound and finds that it is Sebastian Vaughn playing his guitar on the street. Jesse notes that he's heard the song Sebastian is playing before, but Sebastian just chalks it up to Jesse hearing him play it once before.

Liliana invites Sebastian to lunch because, in her opinion, he is way to thin. When they get to the diner they find, rather unexpectedly that everyone ended up going there, each for different reasons.

When Devon announces that she and Gage are having a baby boy and naming him Taylor, after Julia Taylor, everyone drinks to a toast. They marvel at how they've managed to stay together despite all of the obstacles they've faced and they welcome anyone to try and break their little family apart.

2x17: "Give Me One Reason"

Szymon Skubisz sits in the waiting room at the hospital as everyone gets tested to see if they are a match for Sammy’s bone marrow. Ricky Andrews tries to make conversation with him and Szymon asks him how he can still smile when he is surrounded by so much death. Ricky tells him that he chooses to be happy. Joseph Lester admits to Szymon that he actually admires him and will be sorry when Cecilia comes back on full time. He tells Szymon that he is being reassigned to another partner. Joseph and Szymon discuss the nature of evil and whether it runs in the blood. However, when Jesse shows up, Szymon flips out because he doesn’t want Jesse’s blood or bone marrow anywhere near his son. Szymon then begins to take his frustrations out on Cayden when he defends Jesse for showing up to do the right thing.

At the hospital, Cayden approaches Szymon to talk about things, but don’t seem to make much headway. Szymon accused him of spending all of this time and attention on other people. Cayden tells him that he doesn’t want to be around him when he acts like this, but they are interrupted when Jesse arrives and announces that he is a match Sammy’s bone marrow. Cecilia and Andrea arrive. A distraught Szymon tells him that he doesn’t want Jesse’s tainted blood in his son. Jesse says that he always knew Szymon was a hypocrite and that he is willing to let his son die. Szymon says he doesn’t want Jesse’s blood in his son’s body. Liliana tells him that it is too late for that, Jesse is his nephew and she is Szymon’s mother. They have the same blood running through their veins.

Liliana explains to Szymon and Jesse that she gave Szymon up for adoption. He was conceived under duress. She chose not to keep the child. Szymon is horrified and rejects the idea. He calls for a blood test. Liliana tells him that a boy’s life could be hanging in the balance and he will regret it if his stubbornness costs Sammy his life. Szymon expresses his shock at being informed that he is a child of rape. Jesse admits that he is also a child of rape. Szymon is upset that everyone in his life seems to reject him and leave him alone, but Jesse assures him that he won’t be left alone if Szymon agrees to allow him to save Sammy’s life. He will not lose his son.